NKG2D-CAR MEMORY T CELLS TARGET PEDIATRIC T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA IN VITRO AND IN VIVO BUT FAIL TO ELIMINATE LEUKEMIA INITIATING CELLS
Lucía Fernández, National Cancer Research Center, Spain

Authors: M. Ibáñez-Navarro, A.F. Fernández, A. Escudero, G. Esteso, C. Campos-Silva, M.Á. Navarro-Aguadero, A. Leivas, B. Ruz-Caracuel, C. Rodríguez-Antolín, A. Ortiz, A. Navarro-Zapata, C. Mestre-Durán, M. Balaguer- Pérez, C. Ferreras, J. Martínez-López, M. Valés-Gómez, A. Pérez-Martínez, L. Fernández (Spain)

FCYRIIA-SPECIFIC DARPINS DISPLAYED ON VIRAL VECTORS FOR HIV GENE THERAPY
Samuel Theuerkauf, Paul Ehrlich Institute, Germany

Authors: S. Theuerkauf (Germany), A. Jamali (Germany), V. Riechert (Germany), S. Hein (Germany), P. Adams (Netherlands), E. Herrera-Carrillo (Netherlands), B. Berkhout (Netherlands), K. Cichutek (Netherlands), J. Hartmann (Germany), C. Buchholz (Germany)

THE INTEGRATED MULTI-OMIC CHARACTERIZATION OF “OFF-THE-SHELF” CD19-CAR-T CELLS ALLOWS THE IDENTIFICATION OF ENGINEERED CELLS ENDOWED WITH SUPERIOR ANTI-TUMOR FITNESS AND LOWER PRO-INFLAMMATORY ACTIVITY
Cristina Maccalli, Sidra Medicine, Qatar

Authors: A. Al Sulaiti (Qatar), M. El Anbari (Qatar), M. Toufiq (Qatar), S. Jacob (Qatar), S. Kotegar Balayya (Qatar), E. Chin-Smith (Qatar), S. Mohan (Qatar), D. Olagunju (Qatar), C. Cugno (Qatar), S. Deola (Qatar), D. Chaussabel (Qatar), C. Bonini (Italy), M. Casucci (Italy), C. Maccalli (Qatar)

ISOLATION AND CHARACTERIZATION OF NEOEPITOPE-SPECIFIC TCRS FOR T CELL THERAPY IN GASTROINTESTINAL CANCER
Elvira D’Ippolito, Technical University of Munich, Germany

Authors: S. Braun, L. Warmuth, K. Wagner, A. Brutau-Abia, R. Mejías-Luque, M. Gerhard, E. D’Ippolito, D. Busch (Germany)

THIRD-GENERATION CHIMERIC ANTIGEN RECEPTOR (CAR) T CELLS IN ADULT ALL AND NHL PATIENTS
Michael Schmitt, University Hospital Heidelberg, Germany

Authors: M.-L. Schubert, A. Schmitt, A. Hückelhoven-Krauss, B. Neuber, P. Waldhoff, D. Vonficht, S. Yousefian, L. Jopp-Saile, F. Korell, P. Derigs, S. Haas, A.D. Ho, C. Müller-Tidow, P. Dreger, M. Schmitt (Germany)

BANANA LECTIN EXPRESSING CAR T CELLS ENHANCE ANTI-TUMOR ACTIVITY AGAINST HETEROGENOUS SOLID TUMORS
Katie McKenna, Baylor College of Medicine, United States

Authors: K. Mckenna, A. Ozcan, D. Markovitz, M. Brenner (United States of America)

COMBINATION OF CD4+ AND CD8+ T CELLS IN T CELL THERAPY OF HBV INFECTION ENHANCES VIRUS CONTROL IN VIVO BY INCREASING IFN-G AND TNF-A SECRETION
Sophia Schreiber, Technical University of Munich, Germany

Authors: S. Schreiner, S. Schreiber, E. Loffredo-Verde, A. Kosinska, U. Protzer (Germany)

IMMUNOTHERAPY TARGETING MUTANT NUCLEOPHOSMIN-1 ON ACUTE MYELOID LEUKEMIA
Georgia Koutsoumpli, Leiden University Medical Center, Netherlands

Authors: G. Koutsoumpli (Netherlands), D. Van Der Lee (Netherlands), N.C. Groenland (Netherlands), M.W. Honders (Netherlands), R. De Jong (Netherlands), R.S. Hagedoorn (Netherlands), H. Veelken (Netherlands), P. Van Veelen (Netherlands), D. Lock (Germany), M. Heemskerk (Netherlands), J.H.F. Falkenburg (Netherlands), I. Johnston (Germany), M. Griffioen (Netherlands)

SYNTHETIC DUAL-COSTIMULATION FOR TCR AND TCR-LIKE TARGETED CELL THERAPIES
Anton Dobrin, Memorial Sloan Kettering Cancer Center, United States

Authors: A. Dobrin, H. Xie, K. Perica, N. Jain, M. Sadelain, M. Hamieh (United States of America)

THERAPEUTIC GENE EDITING OF T CELLS CORRECTS CTLA4 INSUFFICIENCY
Thomas Fox, University College London, United Kingdom

Authors: T. Fox (United Kingdom), B. Houghton (United Kingdom), L. Petersone (United Kingdom), E. Waters (United Kingdom), N. Edner (United Kingdom), A. Mckenna (United Kingdom), O. Preham (United Kingdom), C. Hinze (United Kingdom), C. Williams (United Kingdom), A. Albuquerque (United Kingdom), A. Kennedy (United Kingdom), A. Pesenacker (United Kingdom), P. Genovese (United States of America), L. Walker (United Kingdom), S. Burns (United Kingdom), D. Sansom (United Kingdom), C. Booth (United Kingdom), E. Morris (United Kingdom)